Four people have been arrested in connection to the death of actor Michael K. Williams in September.

Three of the defendants made a court appearance on Wednesday and a fourth was arrested in Puerto Rico and will appear in court on Thursday in the country where he was arrested.

Recall that Williams, who was best known for his role as Omar Little on HBO’s “The Wire,” was found dead in September 2021 at his New York City apartment.

After thorough investigation, the New York City Medical Examiner’s Office later determined that Williams died from an accidental overdose.

According to court filings, Irvin Cartagena, 39, Hector Robles, 57, Luis Cruz, 56, and Carlos Macci, 70, were arrested on Tuesday and were each charged with “conspiracy to distribute and possess with intent to distribute fentanyl analogue, fentanyl, and heroin.”

The charge carries a mandatory minimum sentence of five years in prison and a maximum sentence of 40 years.

On or about Sept. 5, 2021, the defendants sold Williams the heroin, which was laced with fentanyl and a fentanyl analogue, with Cartagena executing the hand-to-hand transaction.

The 54-year-old Williams, best known for his role as Omar Little on HBO’s “The Wire,” was found dead the next day by family members in his Brooklyn penthouse apartment.

An autopsy later confirmed that Williams died as a result of using fentanyl-laced heroin.

“Deadly opioids like fentanyl and heroin don’t care about who you are or what you’ve accomplished,” said US Attorney Damian Williams in a statement. “They just feed addiction and lead to tragedy. The Southern District of New York and our law enforcement partners will not give up. We will bring every tool to bear. And we will continue to hold accountable the dealers who push this poison, exploit addiction , and cause senseless death.”

Despite knowing that Williams died after being sold their product, officials say the four continued to sell fentanyl-laced heroin, in broad daylight, amidst residential apartment buildings in Brooklyn and Manhattan.

“Michael K. Williams, a prominent actor and producer, tragically overdosed in his New York City apartment from fentanyl-laced heroin,” said U.S. Attorney Damian Williams. “Today, along with our law enforcement partners at the NYPD, we announce the arrests of members of a drug crew, including Irvin Cartagena, the man who we allege sold the deadly dose of drugs to Michael K. Williams.”

“This is a public health crisis. And it has to stop. Deadly opioids like fentanyl and heroin don’t care about who you are or what you’ve accomplished. They just feed addiction and lead to tragedy.”

Williams had previously been open about his battle with drug addiction and called it an everyday struggle.

“A lot of people think that when a person puts down the drugs or the alcohol that all the problems go away,” he once said. “That couldn’t be further from the truth. Drugs and alcohol are not the problem. They are merely symptoms of the problem.”